Organometallic Compounds
eMolecules N-(triethoxysilane-PEG36-PEG3-)-N-bis(PEG3-biotin) | | | 100mg
Broadpharm | N-(triethoxysilane-PEG36-PEG3-)-N-bis(PEG3-biotin) | 100mg | 550804629 | BP-24424 | 98.000 | | | 2884.640 | C129H251N9O54S2Si
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eMolecules Building Block Tool
Medchemexpress LLC 4,7,10-trioxa-3-siladodecan-12-ol, 2,2,3,3-tetramethyl- | 201037-95-8 | >=98.0% | 264.43 g/mol | C12H28O4Si | 1 G
TBDMS-PEG3-OH is a tert-butyldimethylsilyl-protected PEG3 linker with a terminal hydroxyl group. It is supplied as a colorless to light yellow liquid and is used as a short, flexible spacer in medicinal chemistry, linker synthesis, and drug-delivery research.
- tert-butyldimethylsilyl-protected terminal hydroxyl
- three ethylene glycol units (PEG3)
- molecular weight 264.43 g/mol
- chemical formula C12H28O4Si
- CAS number 201037-95-8
- purity >=98.0% (1H NMR)
- appearance colorless to light yellow liquid
- storage: pure form -20°C for 3 years; 4°C for 2 years
Medchemexpress LLC N-Boc-PEG5-bromide | 1392499-32-9 | MFCD31536756 | 98.0% | 400.31 g/mol | C15H30BrNO6 | 1 G
N-Boc-PEG5-bromide is a Boc-protected polyethylene glycol (PEG5) bromide linker reagent used in organic synthesis for assembling antibody-drug conjugate (ADC) and proteolysis-targeting chimera (PROTAC) linkers. It supplies a protected amine and a reactive terminal bromide for nucleophilic substitution and coupling reactions, and is provided at high purity for research use.
- Provides a Boc-protected amine for temporary protection during synthesis.
- Offers a terminal bromide suitable for nucleophilic substitution and coupling reactions.
- PEG5 spacer increases solubility and flexibility in linker constructs.
- High purity appropriate for research and linker assembly.
- Stable under recommended storage conditions for extended shelf life.
Medchemexpress LLC I-PEG5-OH 250mg
I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
eMolecules ChemScene Fmoc-NH-PEG3-CH2CH2COOH 250mg 572245281 CS-W020971 0 000 867062-95-1 MFCD06656471 443 496 C24H29NO7
ChemScene Fmoc-NH-PEG3-CH2CH2COOH 250mg 572245281 CS-W020971 0 000 867062-95-1 MFCD06656471 443 496 C24H29NO7
![Medchemexpress LLC 2-[2-(2-azidoethoxy)ethoxy]ethanol | 86520-52-7 | MFCD09753542 | 98.2% | 175.19 g/mol | C6H13N3O3 | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000300804.png-250.jpg)
Medchemexpress LLC 2-[2-(2-azidoethoxy)ethoxy]ethanol | 86520-52-7 | MFCD09753542 | 98.2% | 175.19 g/mol | C6H13N3O3 | 1 G
Azido-PEG3-alcohol (2-[2-(2-azidoethoxy)ethoxy]ethanol, CAS 86520-52-7) is an azide-terminated PEG3 linker designed for click chemistry conjugations and PROTAC linker assembly. It contains a terminal hydroxyl for further functionalization and an azide group compatible with both copper-catalyzed and strain-promoted azide-alkyne cycloadditions.
- Azide functional group enables CuAAC and SPAAC conjugations.
- PEG3 spacer increases aqueous solubility and flexibility.
- Small molecular weight (175.19 g/mol) minimizes steric hindrance.
- High purity suitable for synthetic applications and conjugation reactions.
- Terminal hydroxyl allows additional derivatization or coupling.
eMolecules Chem-Impex Tetraisopropyl orthotitanate 1kg 686070057 41289 0 000 546-68-9 MFCD00008871 284 219 C12H28O4Ti
Chem-Impex Tetraisopropyl orthotitanate 1kg 686070057 41289 0 000 546-68-9 MFCD00008871 284 219 C12H28O4Ti
Medchemexpress LLC (S,R,S)-AHPC-PEG3-NH2 hydrochloride | 2097971-11-2 | MFCD31656714 | 99.0% | 656.23 g/mol | C30H46ClN5O7S | 1 G
(S,R,S)-AHPC-PEG3-NH2 hydrochloride is a VHL E3 ligase ligand-linker conjugate that combines a stereodefined AHPC VHL ligand with a three-unit polyethylene glycol linker terminating in a primary amine. Supplied as the hydrochloride salt, it is intended as a research building block for PROTAC synthesis and other chemical biology applications.
- Hydrochloride salt form for improved handling.
- Primary amine terminus suitable for common coupling chemistries.
- Three-unit PEG linker provides aqueous solubility and flexible spacing.
- Stereochemically defined (S,R,S) VHL ligand for targeted E3 ligase engagement.
- High reported purity (~99.0%) for reliable synthetic use.
- Available in small to gram-scale quantities for research workflows.
Medchemexpress LLC Tert-butyl 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoate | 252881-73-5 | 303.3547 g/mol | C13H25N3O5 | 50 MG
N3-PEG3-CH2CH2-Boc is an azido-terminated PEG3 linker with a tert-butyl (Boc) protected carboxylic acid end, used as a cleavable PEG-based linker in antibody-drug conjugate and PROTAC synthesis, and as an azide reagent for click chemistry.
- Azide-terminated PEG3 linker suitable for click chemistry.
- tert-Butyl (Boc) protected carboxyl end for orthogonal deprotection.
- Used in ADC and PROTAC linker assembly.
- Available as a small pre-weighed laboratory pack for synthetic use.
Medchemexpress LLC Biotin-PEG3-SS-azide | 2866429-93-6 | 99.6% | 692.91 | C27H48N8O7S3 | 10 MG
Biotin-PEG3-SS-azide is a cleavable three-unit polyethylene glycol linker bearing a biotin group and a terminal azide, designed for conjugation chemistry in research applications. It is suitable for click chemistry reactions and as a cleavable linker in the synthesis of antibody-drug conjugates.
- Cleavable disulfide linker provides intracellular release.
- Azide functionality enables CuAAC and strain-promoted cycloaddition.
- PEG3 spacer increases solubility and reduces steric hindrance.
- High purity supports reliable conjugation results.
- Soluble in DMSO at high concentration for in vitro use.
- Recommended storage at low temperature and protection from light to preserve stability.
Medchemexpress LLC M-PEG5-acid | 81836-43-3 | MFCD20926398 | 95.0% | 280.31 g/mol | C12H24O7 | 1 G
m-PEG5-acid is a monomethylated polyethylene glycol (PEG) linker terminated with a carboxylic acid group, used as a short spacer in the synthesis of PROTACs and other bioconjugates. It provides a PEG5 (approximately five ethylene oxide units) spacer with a reactive carboxylic acid for standard coupling chemistries.
- Short monomethylated PEG5 spacer with terminal carboxylic acid.
- Useful as a linker in PROTAC and conjugate synthesis.
- Molecular weight ~280.31 g/mol and formula C12H24O7.
- Typical purity around 95.0%.
- Light yellow to light brown liquid; density ~1.107 g/cm3.
- Store sealed, away from moisture; use cold storage for solutions.
Medchemexpress LLC Azide-PEG3-tos | 178685-33-1 | 329.37 g/mol | C13H19N3O5S | 250 MG
Azide-PEG3-Tos is a heterobifunctional PEG linker containing an azide functional group for click chemistry. It acts as a non-cleavable, three-unit PEG linker used in the synthesis of PROTACs and antibody-drug conjugates, and participates in copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions.
- Heterobifunctional PEG linker with azide group.
- Molecular weight 329.37 g/mol.
- Chemical formula C13H19N3O5S.
- CAS number 178685-33-1.
- Available in 250 MG packaging; other sizes available.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Applications: PROTAC synthesis, ADC construction, click chemistry.
![Medchemexpress LLC Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester | 186020-66-6 | 95.0% | 278.34 g/mol | C13H26O6 | 25 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202875.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester | 186020-66-6 | 95.0% | 278.34 g/mol | C13H26O6 | 25 G
Hydroxy-PEG3-(CH2)2-Boc is a Boc-protected, hydroxy-terminated polyethylene glycol linker used as a building block in linker and PROTAC synthesis. Supplied as a white to off-white solid, it has a typical purity of 95.0% and a molecular weight of 278.34 g/mol (CAS 186020-66-6).
- Boc-protected hydroxy-terminated PEG3 linker for synthetic chemistry.
- Typical purity 95.0% by NMR.
- Molecular weight 278.34 g/mol.
- Chemical formula C13H26O6.
- Supplied as a 25 g package for laboratory research use only.
TARGETMOL CHEMICALS INC PS-1145 10MG
Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM. Purity 99.63%